Análisis Genético de la Población Ecuatoriana Expuesta a Glifosato
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Abstract
This study analyzes the consequences of aerial spraying with glyphosate and surfactants in the northern part of Ecuador. Chromosome aberration tests and the comet assay were used for human biomonitoring. A total of 24 exposed individuals and 21 controlled individuals were included in the study. The results show significantly higher levels of chromosomal aberrations in the samples of the exposed (22.42%) compared to the controls (1.38%). Similarly, the comet assay showed a high degree of DNA damage in the exposed group (35.5Im) compared to the control group (25.94Im). These results suggest that glyphosate, in the formulation used during aerial spraying, could have a genotoxic effect on exposed individuals.
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CARLlSLE, S. M. & TREVORS, J. T. 1988. Glyphosate in the environment. Water Air Soil Pol/ut, 39:409-420.
U.S. DEPARTMENT OF AGRICULTURE. 2000. Glyphosate. HeIbicide information profile. Forest service pacific northwest region.
BATT, E. D,; BLACK, J. A & COWAN, w. E 1980. The effects ofglyphosate herbicide on chicken egg hatchability. Can J Zool, 58: 1940-1942.
EVANS, D. D. & BATTY, M. J. 1986. Effects of high dietary concentrations of glyphosate on a species of bird, marsupial and rodent indigenous to Australia. Environ Toxico! Chem, 5: 399-401.
GOLDSTEIN, D. A; ACQUAVELLA, J. E; MANNION. R M. & FARMER D. R 2002. An analysis of glyphosate data from the California environmental protection agency pesticide iIIness surveillance program [Abstract]. J Toxico! Clin Toxicol, 40(7):885-892.
WILLlAMS, G M.; KROES. R & MUNRO, 1. C. 2000. Safety evaluation and risk assessment of the herbicide roundup and Íts active ingredient, glyphosate, for humans. Regul Toxico! Pharm, 31: 117-165.
LlOI, M.E.; SCARFI, M. R; SANTORO, A.; BARBIERI, R; ZENI, O.; DI BERARDINO, D. & URSINI, M. V. 1998, Genotoxicity and oxidative stress induced by pesticide exposure in bovine lymphocyte cultures in vitro. Mutat Res, 403:13-20
BOLOGNESI, C. 2003. Genotoxicity of pesticides: A review of human biomonitoring studies. Muta! Res, 543(3):251-272. 9. PAZ Y MIÑO, c.; BUSTAMANTE, G; SÁNCHEZ, M. E. & LEONE, P. 2002. Cytogenetic monitoring in a population occupationalIy exposed to pesticides in Ecuador. Environ. Health Perspect, 110:1077-1080.
MINISTERIO DE RELACIONES EXTERIORES. 2003. Misión de verificación. Impactos en el Ecuador de las fumigaciones realizadas en el departamento del Putumayo dentro del Plan Colombia. Ministerio de Relaciones Exteriores: Ecuador.
ACCIÓN ECOLÓGICA 2003. Impacto de las fumigaciones del Plan Colombia en la frontera ecuatoriana. La guerra oculta contra las comunidades. Acción Ecológica, Quito. Página de Internet: www.accionecoloijica.orij. Consultada 8-junio-2005.
SCARPATO, R.; MIGLlORE, L.; ANGOTZI, G; FEDI, A.; MILlGI, L. & LOPRIENO, N. 1996. CytogeD netic monitoring of a group an Italían floriculturists: No evidence of DNA darnage related to pesticide exposure. Mutat Res, 367:73-82.
SLAMENOV Á, D.; GÁBELOV Á, A; CHALUPA, L; SZABOV Á, E.; MIKUI.ÁSovÁ, M; HORVÁmOVÁ, E.; RUZEKOVA, L.; FARKASOVA, T.; RUPPOVA, K; WSOLOVA, L.; BARANCOKOVA, M. & KAZIMIROVA, A. 1999. Cytotoxic and genotoxíc effect of inhibitor of vulcanization N-cyclohexylthioph.